Kit for Determination of the Maturity of Spermatozoan Nucleoprotein

Aniline Blue Staining Male Infertility Diagnosis

In normal circumstances, the basic protein (nucleoprotein) bound to the sperm nucleus DNA will undergo the process of natural maturity from the histone to protamine, of which, such substitute process of histone by protamine is called nucleoprotein transition, which has an important physiological significance. The spermatozoid nucleus carries all genetic information from paternal, and these genes must start the expression after the fertilization. Before the fertilization, the sperm genes are specially protected by the protamine and closely concentrate with no DNA transcription. However, the abnormality of nucleoprotein transition may cause the male infertility or early embryo abortion. The mechanism lies in: a) the instability in sperm DNA and easily to be damaged and difficult to get pregnant; b) once fertilized, the spermatozoid nucleus cannot normally depolymerized due to the nucleoprotein pattern, and thereby to influence the binding of female and male pronuclei; c) the abnormal development of embryo may induce to the embryo abortion.

This kit is designed for semi-quantitative detection of maturity of human spermatozoan nucleoprotein.

Features:

• A modified method with better repeatability and specificity in test result than competitive products.
• Adjusted by turbidimetry. Not necessary to adjust by the counting of sperm concentration, convenient to operate
• Stable with a shelf life up to one year.
• 40T/Kit, meet the need of batch testing.
• CE approved

The sketch map of test result:

BRED Life Science Technology Inc. specializes in developing, manufacturing and marketing lab products in the field of reproductive medicine, offering automatic assay platform and related products for infertility diagnosis and ART treatment. Based on the test methods and standard recommended by the World Health Organization, BRED develops serial products for infertility diagnosis and ART treatment with innovative technology. And these help promote the establishment and popularization of standardization for reproductive medicine lab. BRED own a completest range of relative products in the field of reproductive medicine worldwide.The products are of independent intellectual property right within BRED.

Our mission of development is to be devoted to providing the best solutions and products for the clinical laboratory in reproductive medicine with the aim to promote the development of human reproductive health.

Our operating philosophy is putting people first, doing business on the basis of honesty, forging ahead and working with diligence.

Welcome to visit our official website: www.spermfunc.com